Signature of Controversy

Dr. Stephen Meyer’s book, Signature in the Cell is an enormous success. It was named one of the New York Times Times Literary Supplement books of the year by a well-respected atheist. It was on Amazon’s top ten science books of 2009. It has been called a “landmark in the intelligent design debate” by a prominent professor of medical genetics, “a ‘must read’ for all serious students of the origin-of-life debate” by an accomplished PhD in ocean chemistry, and a “decisive case based upon breathtaking and cutting-edge science” by a chemistry professor who is a member of the National Academy of Sciences.

Of course the real way you can see how successful the book has been is to read the hysterical reviews from those who disagree with its conclusions. Many of the reviews are quite comical. For example, on this blog I highlighted Dr. Francisco Ayala’s pathetic review where he not only displays his unfamiliarity with genetics, but he also displays the fact that he hasn’t even read the book.

Well, now you can go to one place to find many of these amusing reviews as well as how poorly they fare when they are evaluated based on science: the online book Signature of Controversy. This book is 105 pages of snarky (one section is called “Attack of the Pygmies”), detailed, and scientifically devastating arguments that show how poorly the critics of Signature in the Cell deal with the science related to the origins debate.

In some ways, this book is even better than Signature in the Cell. After all, the case made by Signature in the Cell is very impressive. However, while I was reading it, I kept asking myself, “What will the critics say about this?” After all, if you want to be truly educated on an issue, you must examine it from all sides. Well, with the help of this book, you can see what the critics have to say, and you can see how poorly what they say compares to science as we know it today.

Often, you can judge the quality and impact of a work based on what its critics have to say about it. The weaker and more desperate the critics’ arguments, the stronger and more important the work. Based on the criticisms leveled at Signature in the Cell, it is clearly one of the strongest and most important books related to the origins controversy.

Neanderthals Didn’t…Didn’t…DID Interbreed with People

The original reconstruction of Neanderthal Man (left) and a more realistic reconstruction of a Neanderthal child (right). Both images are in the public domain.

It’s not a really new story, but I was interviewed by an internet radio show about the sequencing of the Neanderthal genome1 and its comparison to present-day people, so I decided I would blog about it as well.

The first thing to discuss is how they sequenced the genome of something that no longer exists. In this case, they used three Neanderthal fossil fragments found in the Vindija cave in Croatia. Fossils (especially those belonging to genus Homo) are rare and very valuable, and this process required the destruction of the fossils, so the three fragments were chosen carefully. They were all fragments that contained very little anatomical information, so anything lost due to the destruction of the fossils was minimal. Based on some pretty good reasoning, it was concluded that the fossil fragments came from three different women, two of which may be relatives. According to scientifically irresponsible dating techniques, these fragments are supposedly around 40 thousand years old.

When they looked at the DNA in the samples they prepared from the bones, they found that between 95 and 99 percent of the DNA came from organisms other than Neanderthals, like bacteria that colonized the fossil. In other words, only 1-5 percent of the DNA found was DNA of interest. How did they get rid of the other 95-99 percent so they could focus on Neanderthal DNA? They used restriction enzymes that tend to cut only bacterial DNA.

So even though this is a remarkable achievement, there are a lot of potential errors in the derived genome sequence. After all, any time the “signal” you are looking at is 20-99 times weaker than the “noise,” it will be hard to determine exactly what the signal is. Keeping in mind these potential errors, what was learned? In short, it was learned that creationists have been right about Neanderthals all along.

Continue reading “Neanderthals Didn’t…Didn’t…DID Interbreed with People”

Smallpox and AIDS?

Components of a smallpox vaccination kit (image in the public domain).

The smartest person with whom I have ever worked sent me a very interesting article from Science Daily. She and I wrote several articles related to the science behind vaccination years ago, and this article is relevant to that issue. It reports on a study published in BMC Immunology, an open-access journal. The results of the study are worth noting.

The researchers studied peripheral blood mononuclear cells (PBMCs) and how susceptible they were to infection by HIV, the virus that causes AIDS. PBMC is the name given to any blood cell that has a round nucleus. Since red blood cells don’t have a nucleus, what this means is that the researchers were looking at certain white blood cells, which are a part of the body’s immune system. Obviously, the susceptibility of white blood cells to HIV is an important issue in the study of AIDS.

Here is the key: they looked at the PBMCs from 10 volunteers who had never been vaccinated against smallpox as well as the PBMCs from 10 volunteers who had been vaccinated against smallpox with a Vaccinia-based vaccine 3 to 6 months prior to the study. Vaccinia is a virus in the poxvirus family that is typically used to produce the immune response to protect against smallpox. Guess what they found.

Continue reading “Smallpox and AIDS?”

The RNA Virus Paradox

A diagram of HIV, which is a retrovirus (image in the public domain)

Dr. Peer Terborg has an incredible series of articles on genetics and the design of life over at Creation Ministries International’s website. The ones to which I refer begin with “Evidence for the design of life…” While I plan to write about many of the major concepts discussed in these articles, I want to start with sort of a “sidelight” that appears in part 3 of his series.

Not too long ago, I wrote about the fact that evolution (in the ‘goo to you’ sense) is, at best, an unconfirmed hypothesis. A commenter, Grant C, tried to convince me that it is something more by offering several lines of evidence for evolution. Of course, I attempted to educate Grant on what the evidence really meant, but after only a few exchanges, he stopped responding.

One of his major lines of evidence for evolution was endogenous retroviral insertions (ERVs) in the genomes of primates. If you don’t know what ERVs are, you need to first learn what a retrovirus is.

Continue reading “The RNA Virus Paradox”

Gut Microbes and Obesity

An obese mouse next to a normal mouse (image in the public domain)

A very interesting study was published in the April 9, 2010 issue of Science.1 In this study, Matam Vijay-Kumar and colleagues experimented with mice, trying to find out how their immune systems interacted with their body weight. Scientists have known for a while that obesity and the immune system are related, but most scientists have thought that obesity causes immune system disorders.2 That might, indeed, be true. However, this study shows that, most likely, immune system disorders can also cause obesity!

Mice (and most vertebrates, including people) have two levels of immunity: innate immunity and adaptive immunity. Innate immunity refers to the mechanisms in the body that protect against general threats. Adaptive immunity refers to the mechanisms in the body that protect against specific threats. So the mechanisms in the body that fight against all bacterial infections are a part of the body’s innate immunity, but when the immune system is attacking a specific species of bacterium, the adaptive immune system is at work.

Matam Vijay-Kumar and colleagues investigated a very specific part of the innate immune system and its effects on obesity in mice. The results were quite surprising.

Continue reading “Gut Microbes and Obesity”

Science Has Demonstrated Evolutionists Wrong and Creationists Right…AGAIN

Schematic of the Human Retina
Illustration by Megan Fruchte

Many evolutionists have claimed that the human eye (actually the vertebrate eye in general) is wired “backwards.” According to evolutionists, this is such a terrible way to make an eye that it clearly shows the eye has no Designer. What is so “terrible” about the way the eye is wired? Well, light that enters the eye is detected by specialized cells called rods and cones. Those rods and cones convert the light that they detect into signals that travel through association neurons and into nerve fibers that carry the signals to the brain. As shown in the illustration above, however, the neurons and nerves that carry those signals are in front of the rods and cones. Thus, light must travel through the nerves and association neurons before it can hit the rods and cones.

According to evolutionists, this is a terrible design. After all, if anyone with any sense were to design an eye, the rods and cones would be the first thing the light hits. That way, the rods and cones would get an unobstructed view of the light. Since the vertebrate eye is not designed the way these evolutionists think should be “obvious,” it is clear (to them) that the eye was not designed. Indeed, in his book The Blind Watchmaker (probably his best work), Richard Dawkins says:

Any engineer would naturally assume that the photocells would point towards the light, with their wires leading backwards towards the brain. He would laugh at any suggestion that the photocells might point away from the light, with their wires departing on the side nearest the light. Yet this is exactly what happens in all vertebrate retinas.1

Of course, like most evolutionary nonsense, the more science we learn, the more we see how wrong this argument is.

Continue reading “Science Has Demonstrated Evolutionists Wrong and Creationists Right…AGAIN”

Babies and Morality

Is morality something that is a part of our very being, or is it something that is learned from our culture? From a scientific point of view, that is a hard thing to answer. Data exist that could support either argument, so often the conclusion that is drawn from the scientific evidence tells us more about the interpreter than the data. A very interesting article in the New York Times illustrates this in very stark terms.

Before I start discussing this article, there are two things I want to make clear. First, I got this article from PZ Myers’s blog. As anyone who reads this blog probably knows, he is my favorite atheist. More than anyone else, he demonstrates how the atheistic worldview is based on irratonaility. As I have written before, there are serious scholars who are atheists, and their arguments need to be heeded. There are also hacks that are atheists, and their arguments make it very easy to be a theist. PZ Meyers is, indeed, one of the hacks. Nevertheless, I read his blog because it is fun to see the mental gymnastics through which a scientist must go in order to be an atheist.

The second thing I want to make clear is that I do not think that the argument from morality is a reasonable argument for the existence of God. While there is ovewhelming scientific evidence for the existence of God, the argument from morality simply isn’t one of them. Indeed, in my experience, some of the most immoral people I know call themselves Christians, and their “morality” is put to shame by many atheists.

So…while I don’t think the argument from morality holds much weight, I do think that the interpretation of any data related to morality (like the interpretation of many other kinds of data) is heavily influenced by whether or not you think God exists. This New York Times story demonstrates that in no uncertain terms.

Continue reading “Babies and Morality”

Is DNA Providing a Coherent View of Evolution?

Darwin's Proposed 'Tree of Life'
source:http://darwin-online.org.uk/life10b.html
Darwin believed that all forms of life existing on this planet arose from “a few…or one”1 form(s) of life. While mulling over this idea, he sketched in one of his notebooks something that has been an icon of evolution ever since: the tree of life. His idea was that if you could properly trace the evolutionary relationships of all organisms, you would find that they would form a “giant tree,” with all the “branches” eventually tracing back to the one or few life forms that started all of evolution. Since that time, evolutionists have been trying to construct such a “tree of life,” but they have met with limited success. The problem is that different methods for constructing the “tree of life” give rather different results. For example, if you look at the morphology (form and structure) of organisms, you construct one “tree.” However, if you look at common molecules, such as the RNA found in a cell’s ribosomes, you get a different “tree.” As Masami Hasegawa and colleagues wrote:

That molecular evidence typically squares with morphological patterns is a view held by many biologists, but interestingly, by relatively few systematists. Most of the latter know that the two lines of evidence may often be incongruent.2

Once scientists got to the point where they could sequence many, many genes and compare the genes in one organism directly to the genes in another organism, it was thought that a “definitive tree of life” would be produced. After all, since evolution is supposed to occur via mutations in the genome being acted on by natural selection, genetics should provide a clear map of how evolution progressed.

The problem is that DNA has simply muddied the waters even more when it comes to evolutionary relationships. Indeed, it has caused some biologists to say that evolution cannot even be represented by a tree.

Continue reading “Is DNA Providing a Coherent View of Evolution?”

Now This is Interesting…

Answers research journal has just published a very interesting study called Baraminological Analysis Places Homo habilis, Homo rudolfensis, and Australopithecus sediba in the Human Holobaramin. If you are not familiar with the term “holobaramin,” it refers to a group of animals that are all related to one another through common descent.

Remember, in the creationist view, God created individual KINDS of organisms, and the genomes of those organisms were created so that they could adjust and adapt to changing conditions. As a result, the organisms that God created could change significantly, but not infinitely. Their amount of change is bound by the level of information in their genomes.

Wolves and dogs, for example, are a part of the same holobaramin. Even though a Chihuahua and a timber wolf might look and behave very differently, they both descended from the same kind of animal created by God. So when a creationist says that certain creatures belong to the same holobaramin, he or she means they both descended from the same created kind of creature.

The analysis presented in the peer-reviewed paper linked above says that Australopithecus sediba should be placed in the human holobaramin, which means it descended from people. If you recall, this is quite different from my analysis of A. sediba.

While the paper does do a solid baraminological analysis, I am not sure I agree with that conclusion. After all, this paper focused only on craniodental features. While I don’t have a problem with that in general, I do have a problem with including Australopithecus sediba in such an analysis. Remember that the majority of the cranial and dental bones recovered were from a juvenile, and it is difficult to compare juveniles with adults. Thus, I am afraid that making a definitive placement for Australopithecus sediba is a bit premature. Hopefully, more fossils will eventually be published so that a more thorough baraminological can take place.

The other conclusion of the paper was quite interesting:

Results indicate that hominins may be divided into as many as four different holobaramins: (1) the genus Homo (including Australopithecus sediba), (2) the genus Paranthropus, (3) Australopithecus africanus, and (4) Gorilla, Pan, Australopithecus afarensis, and Australopithecus garhi.

So Australopithecus africanus is not related to and A. afarensis or A. garhi. That surprises me. However, based on the craniodental data, it seems to be the correct conclusion.