Category: Modern Science

NASA’s Study Indicates Space Changes GENE EXPRESSION, not GENES!

Identical twin astronauts, Scott Kelly (right) and Mark Kelly (left).

Newsweek headlined its article, “Scott Kelly: NASA Study Confirms Astronaut’s DNA Actually Changed in Space.” The article says:

After landing, 93 percent of Scott Kelly’s genes returned to normal, the researchers found. The altered 7 percent, however, could indicate long-term changes in genes connected to the immune system, DNA repair, bone formation networks, oxygen deprivation and elevated carbon dioxide levels.

The Telegraph headline reads, “Nasa astronaut twins Scott and Mark Kelly no longer genetically identical after space trip.” The article states:

But new findings by Nasa have found that life away from planet Earth has exacted a surprising toll. The pair are no longer genetically identical twins.

Please understand that both of these articles are doing what is typical of the modern media when it comes to science. They are taking results that are really, really interesting, and they are hyping the results to the point where they are not telling the truth anymore. NASA did do a wonderful experiment on the genetic effects of being in space a long time, and while the results are quite remarkable, they don’t indicate that space changes a person’s genes. They indicate that space changes the expression of certain genes, and for some, that change is remarkably long-lived.

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When Hysteria is More Important than Science

This is a picture of the Maldives cabinet meeting that took place on October 17th, 2009. (click for credit)

Sea levels have been rising since the early 1800s, and while satellites have only been measuring them since 1992, satellite measurements indicate that they have been rising at a fairly constant rate of 2.8 millimeters per year. This is concerning to many people, especially the ones who live in countries like the Republic of Maldives, which is, on average, only 1.5 meters above sea level. In fact, the country is so concerned about the rising seas that in 2009, the nation’s cabinet held a meeting underwater, where they signed a document calling on all countries to reduce their carbon dioxide emissions. After all, it is thought that rising carbon dioxide levels in the atmosphere warm the planet, which in turn causes sea levels to rise. If sea levels rise too much, the Republic of Maldives will be lost.

Now, of course, that kind of reasoning makes sense, but anyone who studies science should understand that things which make sense are not necessarily true. A lot of Aristotle’s notions (such as the idea that objects prefer to stay at rest) made sense, but science has demonstrated them to be false. In the same way, a lot of our modern theories (like quantum mechanics and relativity) make little sense, but experiments strongly support their conclusions (see here and here, for example).

Rather than giving into the hysteria, then, it is best to see what the data indicate. Interestingly enough, the data say that while the idea that rising sea levels will destroy countries like the Republic of Maldives makes sense, it is almost certainly not true. I first wrote about this three years ago, when a group of researchers decided to study some of the islands around the Funafuti Atoll, which holds the island nation of Tuvalu. They found that contrary to the hysteria, the majority of the islands they studied have grown since 1897, leading to a net increase in the amount of land available. Well, the same research group has completed a more extensive study, which confirms their previous conclusion.

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Possible Physical Evidence of the Prophet Isaiah

King Hezekiah on his sickbed, as described in 2 Kings 20:1-11 (click for credit)

In 2 Kings 18-20, Isaiah 36-39, and 2 Chronicles 29-32, the Bible discusses the reign of King Hezekiah, who had several interactions with the prophet Isaiah. For example, the woodcutting shown above depicts 2 Kings 20:1-11. The king is dying, but the Lord hears his prayer and Isaiah tells him he will be healed. The King asks for a sign, and Isaiah causes a shadow to move in the direction opposite of the direction the sun would make it move.

Several extraBiblical references to King Hezekiah have been found, including a bulla (clay seal impression) bearing the phrase, “Belonging to Hezekiah, (son of) Ahaz, king of Judah.” However, there are no known extraBiblical references to the prophet Isaiah, at least not until now. While it is by no means certain, there is good archaeological evidence that a bulla from the prophet Isaiah has been found in the same area.

As discussed in Biblical Archaeology Review, Eilat Mazar (who also discovered King Hezekiah’s bulla) reports finding several other bullae in the same excavation. One bulla, found only 10 feet from King Hezekiah’s bulla, might very well belong to the prophet Isaiah. As Mazar writes:

Alongside the bullae of Hezekiah and the Bes family, 22 additional bullae with Hebrew names were found. Among these is the bulla of “Yesha‘yah[u] Nvy[?].” The obvious initial translation, as surprising as it might seem, suggests that this belonged to the prophet Isaiah.

It would make sense to find a bulla from Isaiah in the same excavation as bullae from King Hezekiah, but the conclusion is not ironclad. The name is pretty clear, but the last part, “Nvy[?],” is not. According to Mazar, the last part should signify the word “prophet,” but only if there is an aleph (’) at the end (where she put “[?]”). As she says:

Whether or not the aleph was added at the end of the lower register is speculative, as meticulous examinations of that damaged part of the bulla could not identify any remnants of additional letters.

So this bulla might just belong to a person named Isaiah who was not a prophet. However, given the archaeological context of the find, as well as the damaged nature of the artifact, there is at least a strong possibility that it represents the first extraBiblical evidence for the prophet Isaiah.

Facts and Truth

Me as Don Quixote in Man of La Mancha.
This past weekend I did something I have been dreaming about for more than 30 years. I portrayed the lead role in the classic musical Man of LaMancha. It was a wonderful experience. The cast was incredibly talented, and the production was both unique and beautiful. All the performances were sold out, and the audiences truly enjoyed the experience. I cannot express how thankful I am to The Alley Theatre for its support and its love of the arts.

As any serious art should do, the musical tackles a big question: How should we approach the world in which we live? On one side, there is the character Dr. Sanson Carassco, who says that we must face the world as it is. On the other side, there is Don Quixote, who says we should face the world as it ought to be. For example, Don Quixote meets a prostitute named Aldonza. However, he sees and treats her as a virtuous lady he calls “Dulcinea.”

In his insightful program notes, our director said this:

The simple, deconstructed storyline of LAMANCHA can be imagined as DON QUIXOTE standing at one end of a line. He is the dreamer and the crusader for change. On the other end of the line is DR. CARASSCO, the representative of “things as they are.” Walking from one to the other, in journey we should all take, is ALDONZA. She begins as “who she is” and ends as “who she should be and could be.”

While these notes give you the “big picture” about the show’s message, I want to discuss a side issue that centers around one of my favorite lines. When I first started rehearsing, I said the line one way, but our ever-patient director encouraged me to re-examine how Don Quixote would actually say it, and I ended up changing the delivery significantly.

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Cells Have Digital-to-Analog Converters

A schematic representation of the digital-to-analog conversion process.
(click to see credit for unedited image)

Suppose you want to listen to some music. You pull out your iPod or your phone, put the earbuds in your ears, and you start to enjoy your favorite tunes. You probably don’t think about the process that makes this possible: digital-to-analog conversion. Computers and devices based on them store all of their information digitally. On your iPod or phone, the music is stored as a string of 1’s and O’s. The 1’s represent electricity being on, and the 0’s represent electricity being off. So as your iPod or phone “plays” the music, it comes out digitally: as pulses of electricity, either on or off.

If you tried to listen to those pulses, they would make no sense to you, because your ears aren’t designed to hear things digitally. Instead, they are designed to hear sounds in a continuous flow. We call this analog. So while your iPod or phone stores music digitally, it must convert that music into a continuous, analog signal so that you can understand it. It does this with an electrical circuit called a digital-to-analog converter (DAC). Here is a picture of a simple one (click it for credit):

Obviously, the digital-to-analog converter in your phone or iPod is much more sophisticated. It produces a higher-quality analog signal, but probably more importantly, it is packed into a tiny space. That’s what really makes it sophisticated. It can do a complex job while taking up very little room.

It turns out that cells have essentially the same thing, but it is significantly more sophisticated than what you find in an iPod or phone.

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Birds Seem to Intentionally Spread Fires!

Brown Falcons like this one have been observed intentionally spreading fires in Australia.
(click for credit)
Birds are incredibly intelligent animals. They work through certain probability problems better than some students, they communicate with people in order to hunt, they build structures with perspective in mind, they can figure out other birds’ desires, and they use and modify tools. Well, now we have one more thing to add to the list. According to a recent study published in the Journal of Ethnobiology, at least three species of bird (Black Kites, Whistling Kites, and Brown Falcons) also use fire!

It has been known for some time that certain birds of prey tend to congregate near wildfires. Most animals flee from fire, and that’s why the birds are there. After all, the fire is essentially flushing small animals out of the underbrush, making them easy prey for the birds. Now it’s not all that surprising for birds to notice the abundance of easy prey near a fire and eventually figure out that there is an association between fire and prey. However, the authors of this study confirmed something that Aboriginal Australians had known for quite some time – birds actually spread the fires to get even more prey!

This “fire spreading” has been depicted in sacred rituals of the Aboriginal Australians, but many non-Aboriginals have expressed skepticism. As a result, the authors of the study decided to conduct detailed interviews with both Aboriginal and non-Aboriginal Australians to see if they could both confirm the behavior and figure out a pattern to it. Two of them (Ferguson and Eussen) also reviewed their own observations over years of field work in Australia. Based on the interviews and those observations, a pattern emerged.

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Another Evolutionary Idea Falisified

In 1930, Dr. Ronald Fisher (statistician and geneticist) wrote a book entitled, The Genetical Theory of Natural Selection. In that book, he produced a mathematical proof of what he called the “Fundamental Theorem of Natural Selection.” Partly due to his difficult writing style and partly due to a feud in the literature with American geneticist Dr. Sewall Wright, his theorem was misunderstood for quite some time. In 1972, however, physical chemist Dr. George R. Price explained it in a detailed way and showed that it was mathematically correct.

What is the importance of the Theorem and what does it say? This quote from Essential Readings in Evolutionary Biology (by Francisco J. Ayala, John C. Avise, 2014) answers both of those questions:

…Fisher’s formulation of the “fundamental theorem of natural selection,” which would play a preeminent role in the future development of evolutionary genetics: “The rate of increase in fitness of any organism at any time is equal to its genetic variation in fitness at that time.” (p. 73)

In other words, natural selection will cause an organism to increase in fitness as long as its population has variation in the genes associated with fitness. The more variation in those genes, the faster the organism will increase in fitness. As Drs. Ayala and Avise indicate, this theorem became very important in shaping the field of evolutionary genetics.

While Fisher’s fundamental theorem is still quite correct, it is limited. In particular, it doesn’t take the effect of mutations into account. However, there is a corollary attached to the theorem: Since mutations should increase the genetic variation in a population, mutations should lead to a faster rate of fitness increase. While that corollary was important in shaping Neo-Darwinism, a recent paper published in the Journal of Mathematical Biology has shown that it is false when even mildly realistic conditions are considered.

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Bias in Science

An illustration of the differences between RNA and DNA
(click for credit and a larger image)

Several years ago, Dr. Ivan Oransky (MD) and Adam Marcus (MA in science writing) started a blog called Retraction Watch, which reports on scientific papers that have been retracted by the journals that published them or the authors who wrote them. It provides a valuable service to those of us who frequently read the scientific literature, because many journals and authors don’t promote their retractions nearly as much as they promote their papers. Thus, if I want to see whether or not an important publication in the scientific literature has withstood the scrutiny of other scientists, I can check this blog.

Last week, while scanning the new entries, I ran across an interesting one. It reported on a major paper published last year in the journal Nature Chemistry. Despite the fact that it was published only 18 months ago, it has already been cited by 26 other papers in the scientific literature. Why? Because it appeared to solve a very serious problem in what is probably the most popular origin-of-life scenario.

Because the origin-of-life scenario I was taught as fact at university has fallen out of favor among origin-of-life researchers, other scenarios are being explored. One such scenario is the “RNA world” hypothesis. In this view, life was not initially based on DNA. Instead, it was based on a similar molecule, RNA (the differences between the two molecules are shown in the graphic above). This view has garnered a lot of attention, because RNA can do something DNA cannot. It can speed up chemical reactions without being used up in the process.

Why is this important? Many chemical reactions that occur in living systems happen slowly on their own. To be used by a cell, they need to be sped up. Cells do that today with enzymes, and they make those enzymes based on instructions that are found in their DNA. The problem is, of course, that a living system is needed to replicate DNA. But that living system depends on the information stored in DNA. How was DNA originally produced if its very replication is based on the information it contains? The RNA world gets rid of that problem.

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Lightning: A Natural Nuclear Reactor!

A thunderstorm in Annemasse, Haute-Savoie, France (click for full credit info)

In 1994, a scientific team using the Compton Gamma Ray Observatory reported seeing intense gamma ray flashes coming from the earth. The researchers called it an “unexplained terrestrial phenomenon,” but they noted:

The apparent correlation of the events with storm systems leads us to hypothesize that they are caused by electrical discharges to the stratosphere or ionosphere.

This generated interest among certain research groups, so ground-based observatories, airborne detectors, and other space-based observatories began looking for the same thing. It is now well-known that lightning is accompanied by the production of high-energy gamma rays.

While these gamma rays are of high enough energy to induce nuclear reactions, until now there has been no conclusive evidence that such reactions are actually occurring in connection with lightning storms. However, thanks in part to a Japanese academic crowdfunding site, we now have strong evidence that lightning does, indeed, produce nuclear reactions in the atmosphere!

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More Evidence That Bill Nye Has No Idea What He Is Talking About

Bill Nye, the Anti-Science Guy (click for credit)
Bill Nye calls himself “The Science Guy,” but most of his actions are decidedly anti-science. In 2012, he made a video saying that we should censor a scientific idea because it goes against the scientific consensus. He also narrated a faked experiment, demonstrating his ignorance of the physics related to global warming. He published a book about evolution that was riddled with scientific errors. He tried to discuss human reproduction and once again, ended up showing his ignorance. He also contends that the discipline which gave us science is essentially useless. The fact that he is one of today’s spokepersons for science is a frightening indication of this generation’s scientific illiteracy.

As I was preparing to blog about a completely different subject today, I realized that over the past few days, I have come across two more examples that indicate Bill Nye really has no idea what he is talking about, so I decided to put off the topic I was going to discuss and write about those examples instead. One of them relates to the first anti-science action I mentioned above. Nye made a video telling parents to stop thinking for themselves and encouraging their children to think for themselves. Instead, he told them to simply parrot what the High Priests of Science say when it comes to the origin of life and its diversity. Obviously, that is about as anti-science as one can get. Along the way, he made an incredibly ignorant statement about the debate regarding origins:

Denial of evolution is unique to the United States.

As I pointed out previously, that is utter nonsense. There are creationist movements in many, many countries, including Australia, Belgium, Brazil, Canada, France, Germany, Hungary, Italy, Japan, Latvia, Mexico, and the Netherlands. Just a few days ago, however, I blogged about a specific example that comes from Germany. In 2015 Dr. Günter Bechly, a German paleontologist who was the curator of the Stuttgart Museum of Natural History, publicly announced that he thinks Intelligent Design is the best explanation for the origin and diversity of life. The Inquisition was mobilized, and he is no longer the curator of the Stuttgart Museum of Natural History. He is now a Senior Fellow at an Intelligent Design Think Tank, and he spoke at an Intelligent Design conference that was held at Cambridge University.

If denial of evolution were unique to the United States (as the anti-science guy says) Dr. Bechly would not have been “converted” from materialist NeoDarwinism to Intelligent Design, and there would not have been an Intelligent Design conference at one of England’s most famous universities.

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